Quest and reward
Quest: Inflict 25 Poison, 50 Frost, and 75 Burn on a single enemy. At start of Combat, inflict 25 Poison, 50 Frost, and 75 Burn on all enemies.

Quest: Inflict 25 Poison, 50 Frost, and 75 Burn on a single enemy. At start of Combat, inflict 25 Poison, 50 Frost, and 75 Burn on all enemies.
Quest: Inflict 25 Poison, 50 Frost, and 75 Burn on a single enemy. At start of Combat, inflict 25 Poison, 50 Frost, and 75 Burn on all enemies.
This relic has a quest gate. Read the condition and the reward separately, then make sure the comp can complete the condition during a normal run.
Matches come from the relic text, class names, and hero keywords. They are not a win-rate tier list.
Check formations and written guides for the rest of the team, items, and positioning.